Friday, September 28, 2012

Traffic Air Pollution and Heart Disease in Denmark

Traffic air pollution and mortality from cardiovascular disease and all causes: a Danish cohort study (29 page pdf, Ole Raaschou-Nielsen, Zorana Jovanovic Andersen, Steen Solvang Jensen, Matthias Ketzel, Mette Sørensen, Johnni Hansen, Steffen Loft, Anne Tjønneland and Kim Overvad, Environmental Health, Sep. 5, 2012)

Today’s review concerns the link between air pollution from traffic near residences of people in Denmark and heart disease, taking into account the other effects of noise, diet and other items. Results indicate a significant link with air pollution which is lessened in those with a higher diet of fruits and vegetables.  

Key Quotes:

 “air pollution could affect the risk for cardiovascular disease through mechanisms involving systemic oxidative stress and inflammation, which could drive atherosclerosis progression and other long-term effects as well as serve as triggers of events through changes in vascular function”

 “among those living at locations with high NO2 levels, more were single or divorced, were smokers and exposed to environmental tobacco smoke, less physical activity, used hormone replacement therapy and were exposed to a higher noise level”

 “Dietary intake of fruit and vegetables modified the association between NO2 and mortality, so that the association was strongest for people with a low intake of fruit and vegetables and weakest (or absent) among people with a high intake.. A possible mechanism for a protective effect of fruit and vegetables that are rich in antioxidants and related compounds is scavenging of free radicals and reactive oxygen species generated by exposure to air pollution before they can affect vascular function”

 “Traffic air pollution is associated with mortality from cardiovascular diseases and all causes, after adjustment for traffic noise. The association was strongest for people with a low fruit and vegetable intake”
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