Tuesday, August 11, 2015

Can Vitamin E Reduce the Impact of Particulate Matter on the Lungs?

Circulating Levels of Antioxidant Vitamins Correlate with Better Lung Function and Reduced Exposure to Ambient Pollution (Abstract, Cristina Menni, Sarah J. Metrustry, Robert P. Mohney, Sean Beevers, Ben Barratt, Tim D. Spector, Frank J. Kelly, and Ana M. Valdes, American Journal of Respiratory and Critical Care Medicine, May 15, 2015)

Also discussed here: Link between vitamin E, exposure to air pollution (ScienceDaily, May 15, 2015)

And here: Can vitamin E protect lungs from air pollution? (Indo-Asian News Service, May 15, 2015)

Today we review research into the role that vitamins plays in lessening the damage to the lungs that particulate matter plays through oxidative attacks. Results indicate that higher exposure to PM 2.5 and PM10 had lower levels of vitamin E and lower levels of lung function.


Key Quotes:

“These new findings are consistent with previous reports which observed lower levels of vitamin E in people with lung conditions such as asthma…However, we do not yet fully understand which types of particulate pollution specifically damage the lungs or which vitamins best interfere with this pathway to reduce the level of damage,”

“The strongest association both with PM2.5 and FEV was seen with vitamin E. Individuals with a higher exposure to PM2.5 had significantly lower levels of alpha-tocopherol and also had lower lung function. These findings provide further evidence supporting the theory that PM damages lungs through oxidative attack while alpha-tocopherol acts to minimise oxidative injury.”

“looked at the association between lung function and a set of metabolites – chemical signatures circulating in the blood – and between these metabolites and exposure to PM10 and PM2.5”

"The researchers found that individuals with a higher exposure to PM2.5 had significantly lower levels of vitamin E and also had lower lung function”

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